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We are interested in how the transition between interphase and mitosis is regulated. To study mitotic entry, we develop and employ microscopy-based techniques, including FRET-based probes to monitor enzyme activity. In addition to studying the role of individual proteins, we combine experimental approaches with biophysical models to investigate how activation of diverse cellular factors that are required for mitotic progression is coordinated. For more information visit the lab homepage.   –click here-





July 2016

Our PP2A-B56 motif paper

online in Molecular Cell

click here


July 2016

Our two pool BubR1 paper now

online at Nature Communications

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March 2016

Our Cdc20 phosphorylation paper

is now online at

Nature Communications

click here